Be the Doctor and Make the Diagnosis

The EverythingHealth ever popular image challenge from New England Journal of Medicine is good this week because the photo is so interesting (and challenging).  Be greatful your feet do not look like this.  Please make the diagnosis in the comment section and check back tomorrow for the answer.  Is the condition?

1.    Nephrogenic systemic sclerosis
2.    Keratoderma
3.    Poikiloderma
4.